Head‐to‐head comparison of two transcription‐mediated amplification assay versions for detection of hepatitis <scp>B</scp> virus, hepatitis <scp>C</scp> virus, and human immunodeficiency virus <scp>T</scp>ype 1 in blood donors

Abstract

More efficient target capture chemistry in the new TMA assay version significantly improved sensitivity and diminished variability in detecting HBV strains of various genotypes. We recommend a triplicate ID-NAT repeat test strategy to eliminate discriminatory tests on false-non-repeat-reactive (anti-HBc-nonreactive) donations.