Gestational diabetes mellitus is associated with TCF7L2 gene polymorphisms independent of HLA‐DQB1*0602 genotypes and islet cell autoantibodies

Abstract

The TCF7L2 was associated with susceptibility for gestational diabetes independently of the presence of HLA-DQB1*0602 and islet cell autoantibodies and other factors such as maternal age, number of pregnancies, family history of diabetes and other HLA-DQ genotypes. The HLA-DQB1*0602 was negatively associated with gestational diabetes in mothers born in Sweden.