Concepedia

Friedländer annulation: scope and limitations of metal salt Lewis acid catalysts in selectivity control for the synthesis of functionalised quinolines

Babita Tanwar, Dinesh Kumar, Asim Kumar, Md. Imam Ansari, Mohammad Mohsin Qadri, Maulikkumar D. Vaja, Asit K. Chakraborti

New Journal of Chemistry · 2015 · 25 citations · 56 references

DOI

Concepts

Abstract

In(OTf)<sub>3</sub> is the most effective catalyst among metal halides, tetrafluoroborates, perchlorates, and triflates for Friedländer quinoline synthesis in 75–92% yields.

References

56

A New Series of PDGF Receptor Tyrosine Kinase Inhibitors: 3-Substituted Quinoline Derivatives

Martin P. Maguire, Kimberly R. Sheets, Karen McVety et al. · Journal of Medicinal Chemistry · 1994 · 440 citations · Full text

, , +12

Chemoselectivity: The Mother of Invention in Total Synthesis

Ryan A. Shenvi, Daniel P. O’Malley, Phil S. Baran · Accounts of Chemical Research · 2009 · 339 citations · Full text

, , +14

Synthesis, properties, and reactions of bis((trifluoromethyl)sulfonyl) imide, (CF3SO2)2NH

Jerry Foropoulos, Darryl D. DesMarteau · Inorganic Chemistry · 1984 · 338 citations

, , +5

A Mild and Efficient One-Step Synthesis of Quinolines

Brian R. McNaughton, Benjamin L. Miller · Organic Letters · 2003 · 335 citations

, , +7

An Extremely Efficient Three-Component Reaction of Aldehydes/Ketones, Amines, and Phosphites (Kabachnik−Fields Reaction) for the Synthesis of α-Aminophosphonates Catalyzed by Magnesium Perchlorate

Srikant Bhagat, Asit K. Chakraborti · The Journal of Organic Chemistry · 2007 · 321 citations

, , +13