ADENOSINE 3' 5'-CYCLIC MONOPHOSPHATE PHOSPHODIESTERASE IN SKIN.

Abstract

Summary.— The activity of cAMP phosphodiesterase under conditions of substrate saturation (Vmax) and its substrate affinity (Km) were measured in biopsy specimens from the lesions of atopic dermatitis, from atopic uninvolved skin, and from the skin of healthy controls. No significant difference was found between the atopic and the control specimens.