PEDIATRICS · 1964 · 40 citations · 0 references
MedicineChild HealthPediatricsNeonatal HealthNeonatologyTransfusion MedicineBlood Transfusion ManagementNeonatal HematologyNeonatal TransfusionPediatric TransfusionBilirubin EncephalopathyBinding CapacityBlood Transfusion TherapyNeonatal Exchange TransfusionNeonatal Transfusion TherapyTransfusion In Premature InfantsTransfusion IndicationsTransfusion Medicine In Children
Maternal titer, history of previously treated sibling, positive Coombs, prematurity, cord serum bilirubin, and hemoglobin concentration do not by themselves indicate the need for immediate exchange transfusion in an infant who shows no signs of disease. The measurement of the reserve albumin binding capacity is a useful aid in determining the need for exchange transfusion in preventing bilirubin encephalopathy. A delay in treatment of infants who have an adequate reserve binding capacity does not increase the need for re-exchange and avoids unnecessary procedures. The rate of re-exchange among infants receiving added albumin and managed according to the criteria outlined was lower than in the conventionally treated series.