Nod1, Nod2 and Nalp3 receptors, new potential targets in treatment of allergic rhinitis?

Abstract

Nod1, Nod2, and Nalp3 receptors were found to be present in the human nose. The expression of Nod1 and Nalp3 were down-regulated during pollen season among patients with allergic rhinitis. This opens up for new insights and novel therapeutic strategies in inflammatory airway disease.