Effects of flunixin meglumine and dexamethasone on aqueous protein values after intraocular surgery in the dog

Abstract

Effects of flunixin meglumine and/or dexamethasone on aqueous protein concentrations were evaluated in dogs during and after intraocular surgery. Flunixin meglumine plus dexamethasone had the greatest inhibitory effect on postoperative aqueous protein increases with 64.2% inhibition over base-line aqueous protein values 24 hours after surgery. Dexamethasone alone had a 45.6% inhibition and flunixin meglumine alone had a 22.4% inhibition. Treatment with these drugs separately or in combination had a marked effect in decreasing postoperative inflammation.