Circulating levels of citrullinated and MMP-degraded vimentin (VICM) in liver fibrosis related pathology.

Abstract

We demonstrated increased serological levels of citrullinated and MMP degraded vimentin in an animal model of liver fibrosis and in early fibrosis associated with HCV and NAFLD patients. These data suggest that citrullinated and MMP degraded proteins are also present in liver fibrosis.