The added value of quantitative analysis of on‐therapy impedance‐pH parameters in distinguishing refractory non‐erosive reflux disease from functional heartburn

Abstract

Quantitative analysis of impedance-pH parameters added to symptom-reflux association allows a subdivision of refractory-heartburn patients into refractory NERD and FH which is substantiated by pathophysiological findings and which restricts the diagnosis of FH to one third of cases.