Tissue and intracellular pH in normal periarticular soft tissue and during different phases of antigen induced arthritis in the rat.

Abstract

In this model there is a reduction in pH in the periarticular tissue of arthritic joints. The magnitude is, however, relatively small and the pannus tissue is not uniquely acidic in comparison with other compartments. There does not seem to be a correlation between pH and changes in metabolic balance, pannus formation, or healing.