Effect of radiosynovectomy with holmium-166 ferric hydroxide macroaggregate on adult equine cartilage.

Abstract

166Ho-FHMA treatment did not markedly affect the composition or morphology of adult articular cartilage showing mild degeneration. However, minor degradation of proteoglycan monomers and transient downregulation of pro-a1(II) collagen mRNA were observed.