<i>BRAF V600E</i> mutations are frequent in dysembryoplastic neuroepithelial tumors and subependymal giant cell astrocytomas

Abstract

Our data indicate that BRAF(V600E) is a common genetic alteration in low-grade glial tumors with neuronal component or differentiation. High frequency of BRAF(V600E) in DNTs and SEGAs would be useful in the differential diagnosis, and also offers a potential specific treatment targeting BRAF(V600E) .