End‐Stage Renal Disease in African Americans With Lupus Nephritis Is Associated With <i>APOL1</i>

Abstract

APOL1 G1/G2 alleles strongly impact the risk of LN-ESRD in African Americans, as well as the time to progression to ESRD. The high frequency of these alleles in African Americans with near absence in European Americans explains an important proportion of the increased risk of LN-ESRD in African Americans.