Inactivation of <i><scp>P</scp>lasmodium falciparum</i> in whole blood by riboflavin plus irradiation

Abstract

Riboflavin plus irradiation treatment of whole blood damages parasite genomes and drastically reduces P. falciparum viability in vitro. In the absence of suitable malaria screening assays, parasite inactivation should be investigated for prevention of transfusion-transmitted malaria in highly endemic areas.