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Thyroid uptake and imaging with iodine-123 at 4-5 hours: replacement of the 24-hour iodine-131 standard.
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1985
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Parathyroid DiseaseLogistical AdvantagesParathyroid GlandThyroid UptakeIodine Deficiency DisordersParathyroid Hormone4-5 HoursClinical ChemistryLaboratory MedicineRadiation OncologyNuclear MedicineRadiologyHealth SciencesMedical ImagingThyroid DiseaseHr Interval24-Hour Iodine-131 StandardThyroid HormoneMedicineUptake Measurement
A study was carried out to determine the suitability of utilizing a 4 to 5 hr interval from administration of iodine-123 to imaging and uptake measurement as a replacement for the 24-hr standard originally established with iodine-131. In 55 patients who underwent scintigraphy at 4 and 24 hr, there was no discrepancy between paired images. In 55 patients who had uptake measured at 4 and 24 hr and in 191 patients who had uptake measured at 5 and 24 hr, the early measurements proved equal or better discriminants of euthyroid from hyperthyroid patients. In our institutions, these findings and the logistical advantages of completing the exam in 4-5 hr led us to abandon the 24-hr study in the majority of patients.