Facile and expedient access to bis-coumarin–iminothiazole hybrids by molecular hybridization approach: synthesis, molecular modelling and assessment of alkaline phosphatase inhibition, anticancer and antileishmanial potential

Abstract

A series of new cytotoxic bis-coumarin–iminothiazole hybrids was developed as potential inhibitors of alkaline phosphatase and leishmaniasis.