<i>RHD</i>*<i>DOL1</i> and <i>RHD</i>*<i>DOL2</i> encode a partial D antigen and are in cis with the rare <i>RHCE</i>*<i>ceBI</i> allele in people of African descent

Abstract

The rare RHCE*ceBI allele appears to be in cis either with RHD*DOL1 or with RHD*DOL2 in people of African descent. DOL-1 and DOL-2 must be considered as partial D antigens. We recommend a systematic search for RHD*DOL1 and RHD*DOL2 in people found to carry RHCE*ceBI and vice versa, especially in patients with sickle cell disease.