THE ACTION OF ACETIC ANHYDRIDE AND PYRIDINE ON AMINO ACIDS

Abstract

In our first communication on this subject,l we reported the formation of unexpected derivatives of tyrosine and of phenylaminoacetic acid.In the early experiments with tyrosine, the crude reaction product appeared to have been obtained in a purer condition when the preparation was carried out in the presence of acetone.It therefore seemed possible that acetone took part in the reaction.Two possible structural formuls were then given for the compound.However, in the experiment with phenylaminoacetic acid there was observed an abundant evolution of carbon dioxide.Hence, for this derivative two alternative formuhe were given.