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Test for carcinogenicity of organic contaminants of United States drinking waters by pulmonary tumor response in strain A mice.
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1977
Year
PathologyUnited StatesChemical ContaminantEnvironmental ChemistryRespiratory ToxicologyEnvironmental HealthToxicologyPublic HealthLung AdenomasPulmonary Adenoma ResponsePulmonary Tumor ResponseLung DepositionWater QualityChemical PollutionPharmacologyLung CancerInhalation ToxicologyMultiple I.pEnvironmental EngineeringEnvironmental ToxicologyMedicineOrganic Contaminants
The production of lung adenomas in strain A following multiple i.p. injections of selected organic water contaminants was investigated. Of the 16 contaminants tested, only bromoform produced a pulmonary adenoma response that was significantly greater than the pulmonary adenoma response of vehicle-treated control mice.