Human cell culture: morphology of the Detroit strains.

Abstract

Summary The similarities of various Ep-L cell strains derived from cancerous and noncancerous human sources have been described. Variations in cell morphology, polyploidy, and heteroploidy have been found to exist in similar degree in all strains. The morphogenesis of Ep-L cells from Fb-L cells was pointed out, and attempts to identify cell types by various methods were described. The significance of the findings was discussed.