Eco-friendly and Efficient Synthesis of Pyrano[2,3-<i>d</i>] pyrimidinone and Tetrahydrobenzo[<i>b</i>]pyran Derivatives in Water

Abstract

Tetrahydrobenzo[b]pyran and pyrano[2,3-d]pyrimidinone derivatives were synthesized efficiently in the presence of KAl(SO4)2.12H2O (alum) in water. Green media, lack of toxicity, short reaction times, easy work-up and high yields are some advantages of this method.