Concepedia

Effect of addition of statins to antiviral therapy in hepatitis C virus–infected persons: Results from ERCHIVES

Adeel A. Butt, Yan Peng, Hector Bonilla, Abdul‐Badi Abou‐Samra, Obaid S. Shaikh, Tracey G. Simon, Raymond T. Chung, Shari S. Rogal

Hepatology · 2015 · 108 citations · 41 references

DOI

Abstract

Statin use was associated with improved virological response (VR) rates to antiviral therapy and decreased progression of liver fibrosis and incidence of HCC among a large cohort of HCV-positive Veterans. These data support the use of statins in patients with HCV.

References

41

FIB-4

Anaïs Vallet‐Pichard, Vincent Mallet, Bertrand Nalpas et al. · Hepatology · 2007 · 2K citations · Full text

Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids

Sharookh B. Kapadia, Francis V. Chisari · Proceedings of the National Academy of Sciences · 2005 · 497 citations · Full text

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Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial

Satoshi Kawata, Edna N. Yamasaki, T. Nagase et al. · British Journal of Cancer · 2001 · 355 citations · Full text

Different anti-HCV profiles of statins and their potential for combination therapy with interferon

Masanori Ikeda, Kenichi Abe, Masashi Yamada et al. · Hepatology · 2006 · 310 citations · Full text

Efficacy and safety of high-dose pravastatin in hypercholesterolemic patients with well-compensated chronic liver disease: Results of a prospective, randomized, double-blind, placebo-controlled, multicenter trial

James H. Lewis, Mary Ellen Mortensen, Steven Zweig et al. · Hepatology · 2007 · 306 citations · Full text