Clinical implications of family history of prostate cancer and genetic risk single nucleotide polymorphism ( <scp>SNP</scp> ) profiles in an active surveillance cohort

Abstract

There is currently insufficient data to support the use of FH status or prostate cancer SNP profile risk scores as prognostic factors in AS and these should not be used to influence management decisions. As more genetic variants are discovered this may change and should be reassessed in multicentre AS cohorts.