The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin

SMART: a web-based tool for the study of genetically mobile domains

J. Schultz · Nucleic Acids Research · 2000 · 1.4K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

XRCC1 Polypeptide Interacts with DNA Polymerase   and Possibly Poly (ADP-Ribose) Polymerase, and DNA Ligase III Is a Novel Molecular 'Nick-Sensor' In Vitro

Keith W. Caldecott, Saïd Aoufouchi, Peter Johnson et al. · Nucleic Acids Research · 1996 · 612 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

XRCC1 Stimulates Human Polynucleotide Kinase Activity at Damaged DNA Termini and Accelerates DNA Single-Strand Break Repair

Claire J Whitehouse, Richard Taylor, Angela Thistlethwaite et al. · Cell · 2001 · 604 citations · Full text

Life Sciences, Genetics, Molecular Biology +9

Early-onset ataxia with ocular motor apraxia and hypoalbuminemia is caused by mutations in a new HIT superfamily gene

Hidetoshi Date, Osamu Onodera, Hajime Tanaka et al. · Nature Genetics · 2001 · 384 citations

Life Sciences, Genetics, Neurology +11

Molecular Cloning of the Human Gene, PNKP, Encoding a Polynucleotide Kinase 3′-Phosphatase and Evidence for Its Role in Repair of DNA Strand Breaks Caused by Oxidative Damage

Arshad Jilani, Dindial Ramotar, Carolyn Slack et al. · Journal of Biological Chemistry · 1999 · 295 citations · Full text

Life Sciences, Genetics, Molecular Biology +11