Frequent Detection of Hepatitis B Virus X-Gene DNA in Hepatocellular Carcinoma and Adjacent Liver Tissue in Hepatitis B Surface Antigen-Negative Patients

Avoiding false positives with PCR

Shirley Kwok, Russell Higuchi · Nature · 1989 · 3.5K citations

Medicine, Diagnostic Test, Diagnosis +6

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

Chang‐Min Kim, K. Koike, Izumu Saito et al. · Nature · 1991 · 1.2K citations

Hepatology, Viral Hepatitis, Liver Physiology +11

Risk Factors for Hepatocellular Carcinoma among Patients with Chronic Liver Disease

Hideaki Tsukuma, Tomohiko Hiyama, Sachiko Tanaka et al. · New England Journal of Medicine · 1993 · 1.1K citations · Full text

Hepatitis C virus infection is associated with the development of hepatocellular carcinoma.

Izumu Saito, Tatsuo Miyamura, Akira Ohbayashi et al. · Proceedings of the National Academy of Sciences · 1990 · 1.1K citations · Full text

Immunology, Pathology, Cirrhosis +16

Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma

Jian Wang, Xavier Chenivesse, Berthold Henglein et al. · Nature · 1990 · 665 citations

Hepatology, Viral Hepatitis, Immunology +9