Treatment of recurrent antibiotic-associated pseudomembranous colitis.

Abstract

Eleven patients with relapses of antibiotic-associated pseudomembranous colitis were treated with a tapering dose schedule of vancomycin and cholestipol. All patients responded and have continued to be asymptomatic for follow-up periods of at least 6 wk. This tapering dose of vancomycin in conjunction with cholestipol appears to be warranted in patients with relapses of antibiotic-associated pseudomembranous colitis.