The 3′ Part of the Dopamine Transporter Gene<i>DAT1/SLC6A3</i>Is Associated With Withdrawal Seizures in Patients With Alcohol Dependence

Abstract

The present study adds evidence for a significant role of the 3' part of the DAT1 gene in WS of alcohol-dependent patients, not only because it is in accordance with previous work, but also because of larger statistical power (as relying on a sample over sampled with the studied phenotype), as it gives a more precise analysis of different SNPs within the DAT1 gene, and as it confirms the association when major potentially confounding factors are taken into account in a logistical regression analysis.