American Journal of Psychiatry · 1985 · 342 citations · 10 references
Social SciencesPsychiatryPsychologyPsychiatric PharmacotherapyPsychopharmacologyPsychophysiologyAntidepressant TherapyDaylight StudiesDepressionDepressive DisordersMoodPhotoperiodic EndocrinologyAntidepressant EfficacyAntidepressant MedicationsAntidepressant ResponseBalanced Crossover DesignsBright Light ExposureDiurnal Lighting CyclesLight-dark Cycle ResponsesSeasonal Affective Disorder Treatment
The authors treated winter depression in 13 patients with typical seasonal affective disorder by extending the length of winter days with bright and dim light in the morning and evening in a balanced-order crossover study. Bright light had a marked antidepressant effect, whereas the dim light did not. This response could not be attributed to sleep deprivation. Subsequent pilot studies indicated that bright evening light alone is probably also effective. Several patients were able to maintain the antidepressant response throughout the winter months by continuing daily light treatments.
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