Physiological characterization of mBSA antigen induced arthritis in the rat. I. Vascular leakiness and pannus growth.

Abstract

Proliferative response follows the inflammatory vascular inflammation over time. The knee diameter, which is the most commonly used clinical measurement, seems mainly to be a reflection of the former variable. The effects of MTX and indomethacin suggest that the pannus formation is induced by the inflammatory activity in this model.