Concepedia

Publication | Closed Access

Inhibitor of nuclear factor ?B kinase ? is a key regulator of synovial inflammation

DOI

232

Citations

35

References

2001

Year

Paul P. Tak, Daniëlle M. Gerlag, Karl R. Aupperle, Deliana A. Van De Geest, Marieke J. Overbeek, Brydon L. Bennett, David L. Boyle, Anthony Manning, Gary S. Firestein
Arthritis & Rheumatism

Abstract

IKKbeta plays a key role in rodent synovial inflammation. Intraarticular gene therapy to inhibit IKKbeta activity represents an attractive strategy for the treatment of chronic arthritis.

References

YearCitations

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