Synthesis and Evaluation of Novel Ferrocenyl Thiazole Derivatives as Anticancer Agents

Abstract

Novel ferrocenyl‐containing thiazole derivatives have been synthesized from 2‐amino‐4‐ferrocenyl‐5‐(1H‐1,2,4‐triazole‐1‐yl)‐1,3‐thiazole and substituted benzoyl chloride. The structures of these compounds have been characterized by 1H NMR, elemental analysis and X‐ray diffraction analysis. Evaluation of anticancer activities showed that some of them possessed some degree of anticancer activity.