Effects of receptor tyrosine kinase inhibitors on <scp>VEGF</scp><sub>165</sub>a‐ and <scp>VEGF</scp><sub>165</sub>b‐stimulated gene transcription in <scp>HEK</scp>‐293 cells expressing human <scp>VEGFR</scp>2 - Concepedia

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Effects of receptor tyrosine kinase inhibitors on <scp>VEGF</scp><sub>165</sub>a‐ and <scp>VEGF</scp><sub>165</sub>b‐stimulated gene transcription in <scp>HEK</scp>‐293 cells expressing human <scp>VEGFR</scp>2

DOI Full Paper Access

13

Citations

22

References

2015

Year

Joanne J. Carter, Amanda J. Wheal, Stephen J. Hill, Jeanette Woolard

British Journal of Pharmacology

Abstract

Quantitative pharmacological analysis of the interaction of VEGF(165) isoforms and RTKIs with VEGFR2 in intact living cells has provided important insights into the relative affinity and efficacy of VEGF(165)a and VEGF(165)b for activation of the calcineurin- NFAT signalling pathway by this tyrosine kinase receptor.

References

	Year	Citations

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