Anatomic and anesthetic considerations in experimental cardiopulmonary surgery in swine.

M. Michael Swindle, Peter J. Horneffer, Timothy J. Gardner, V. L. Gott, T S Hall, R. Scott Stuart, Werner A. Baumgartner, A. Michael Borkon, Edgar B. Galloway, Beverly A. Reitz

PubMed · 1986 · 90 citations · 0 references

Concepts

Abstract

We have used immature commercial swine (13-25 kg) successfully in a variety of experimental cardiopulmonary surgical procedures in our laboratories since 1981. Multiple drug anesthetic protocols using barbiturates, narcotics, paralytic and antiarrhythmic agents have been employed in over 400 procedures per year. Complications, including fatal cardiac arrhythmias, have been greatly reduced by anesthetic protocols and surgical procedures developed through experience.