Evidence for involvement of central vasopressin <scp>V</scp>1b and <scp>V</scp>2 receptors in stress‐induced baroreflex desensitization

Abstract

Vasopressin by the stimulation of central V1b- and V2-like receptors mediates stress-induced tachycardia and BRR desensitization. If these mechanisms are involved, BRR desensitization in heart failure and hypertension associated with poor outcome, they could be considered as novel targets for cardiovascular drug development.