PubMed · 2011 · 34 citations · 9 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryHypersensitivityJoint Replacement SurgeryOrthopedicsInterface DermatitisJoint DiseaseJoint Replacement MaterialsMetallic BiomaterialsCobalt Allergic Contact DermatitisMetal Allergy TestingMetal HypersensitivityMetal Ion ReleaseMetal-induced DermatitisTitanium Implant MaterialsTitanium MaterialsZirconium Alloys
Materials currently used for total knee arthroplasty (TKA) are well known for their good biocompatibility, but corrosion of the implant and metal ion release may elicit an immune response in the periprosthetic tissue. Its role in the outcome of the implant remains a subject of discussion. Metal sensitivity after joint replacement is frequent, but few patients exhibit symptoms. Nickel, cobalt and chromium are the most common sensitizers, but allergic reactions to titanium and vanadium have also been described. We present a case of a 46-year old woman with persistent dermatitis following TKA revision with an oxidized zirconium (oxinium) femoral component and Ti6Al4V tibial baseplate. After revision with a customized oxinium tibial component, symptoms resolved completely.
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Sensitivity to implant materials in patients with total knee arthroplasties
Donatella Granchi, E. Cenni, Domenico Tigani et al. · Biomaterials · 2007 · 186 citations