PubMed · 1976 · 12 citations · 0 references
PharmacyPharmacologyPharmacotherapyEndocrine PharmacotherapyNeuroendocrinologyParenteral Drug DeliveryAdrenal DisordersAdrenal Steroid HormonesCorticosteroid TherapyDrug AbsorptionSteroid PharmacologyTopical PreparationsCorticosteroid-induced Striae ManagementTopical ApplicationTopical Corticosteroid PharmacologyTopical Corticosteroid PreparationsTopical Steroid TherapyTreatment With Topical Corticosteroids
A 21-year-old woman developed huge atrophic striae in the axillary and inguinal areas from the topical application, with occlusion, of potent corticosteroid preparation applied to the axillary or inguinal areas. It is postulated that the mechanism is systemic absorption of enough medication to produce a state of hyperadrenalism with subsequent striae formation as a sequela.