Long-term effects of alloxan in mice

Diabetogenic action of streptozotocin: relationship of dose to metabolic response

Alain Junod, André Lambert, W. Stauffacher et al. · Journal of Clinical Investigation · 1969 · 937 citations · Full text

Medicine, Endocrinology, Pharmacology +12

The Generation of Hydrogen Peroxide, Superoxide Radical, and Hydroxyl Radical by 6-Hydroxydopamine, Dialuric Acid, and Related Cytotoxic Agents

Gerald Cohen, Richard E. Heikkila, With the technical assistance of Dana MacNamee · Journal of Biological Chemistry · 1974 · 896 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

Hiroshi Yamamoto, Yasuko Uchigata, Hiroshi Okamoto · Nature · 1981 · 529 citations

Life Sciences, Biochemistry, Molecular Biology +16

Determinants of the selective toxicity of alloxan to the pancreatic B cell.

Willy Malaisse, F Malaisse-Lagae, Abdullah Sener et al. · Proceedings of the National Academy of Sciences · 1982 · 282 citations

Life Sciences, Biochemistry, Pharmacology +17

Superoxide dismutase is a prophylactic against alloxan diabetes

Kjell Grankvist, Stefan L. Marklund, Inge‐Bert Täljedal · Nature · 1981 · 164 citations

Life Sciences, Biochemistry, Endocrinology +13