Ivermectin and Milbemycin Oxime in Experimental Adult Heartworm ( <i>Dirofilaria immitis</i> ) Infection of Dogs

Abstract

Two currently approved macrocyclic lactone HW preventives used at their labeled dose rates were <100% effective against a recent HW field isolate, supporting the hypothesis that the effectiveness of a single dose of these preventives can vary. This is important in guiding clients on expectations of product effectiveness.