NASA Technical Reports Server (NASA) · 1977 · 110 citations · 0 references
Life SciencesBiochemistryPhysiologyBone MetabolismMetabolic PhysiologyMetabolismElectrolyte BalanceElectrolyte HomeostasisElectrolyte ImbalancesMetabolic HomeostasisMineral BiochemistryMineral PhysiologyBiochemical Stress ResponsesBone Mineral DensityBone Mineral HomeostasisBone Mineral LossElectrolyte MonitoringFluid-electrolyte Balance
Continuous metabolic and endocrinic monitoring of Skylab crewmen established significant biochemical changes that varied in magnitude and direction but disappeared shortly after return to earth. These changes indicate adaptation by the body to the combined stresses of weightlessness. Transient changes in fluid and electrolyte metabolisms lead to the conclusion that a homeostasis condition had been achieved. Unstable states persisted in the metabolisms of bone mineral, protein, and carbohydrates.