Profound hypoglycemia with the addition of a tricyclic antidepressant to maintenance sulfonylurea therapy [published erratum appears in Am J Psychiatry 1987 Nov;144(11):1521]

Abstract

Cases of profound hypoglycemia after the initiation of tricyclic antidepressant therapy in two patients taking sulfonylureas are described. To the authors' knowledge, this is the first report of a potential drug interaction between tricyclic antidepressants and sulfonylureas.