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Trimethoprim-sulfamethoxazole-induced cholestasis.
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1981
Year
52-Year Old WomanHepatologyLiver InjuryTmp-smz UseLiver PhysiologyBiliary CancerPharmacologyBiliary TractPathologyPrimary Sclerosing CholangitisHepatotoxicityBiliary DisorderPrimary Biliary CirrhosisMedicineDrug-induced Liver Injury
A 52-year old woman developed severe cholestasis seven days after the administration of trimethoprim-sulfamethoxazole (RMP-SMZ) The clinical and pathologic features are discussed as well as the various mechanisms of liver injury following TMP-SMZ use.