PubMed · 1981 · 20 citations · 0 references
MedicinePathobiologyPharmacotherapyHepatic PharmacotherapyHepatologyBiliary Tract DiseaseBiliary Tract DisordersCholestatic Liver InjuryHepatic ToxicityHepatobiliary DiseaseLiver DiseaseCholestasis PathophysiologyCholestatic JaundiceInflammatory Liver InjuryLiver Injury ResponseMechanismsTrimethoprim-sulfamethoxazole Therapy
A 52-year old woman developed severe cholestasis seven days after the administration of trimethoprim-sulfamethoxazole (RMP-SMZ) The clinical and pathologic features are discussed as well as the various mechanisms of liver injury following TMP-SMZ use.