Concepedia

Characterization of Ocular Pharmacokinetics of Beta-Blockers Using a Diffusion Model After Instillation

Kenzo Yamamura, Hitoshi Sasaki, Mikiro Nakashima, Masataka Ichikawa, Takahiro Mukai, Koyo Nishida, Junzo Nakamura

Pharmaceutical Research · 1999 · 24 citations · 17 references

Concepts

MedicinePharmacokineticsPharmacologyBioavailabilityOcular PharmacologyPharmacokinetic ModelingOcular BioavailabilityOcular Drug MetabolismOcular PharmacodynamicsOcular PharmacokineticsDrug Transport Across Ocular TissuesIntraocular PharmacokineticsOcular Drug AbsorptionOcular Drug Clearance MechanismsOphthalmic Pharmacokinetics

References

17

Lacrimal and Instilled Fluid Dynamics in Rabbit Eyes

Sukhbir S. Chrai, Thomas F. Patton, Ashok K. Mehta et al. · Journal of Pharmaceutical Sciences · 1973 · 349 citations

Pharmacy, Ophthalmology, Pharmacokinetics +14

Physicochemical Determinants of Drug Diffusion Across the Conjunctiva, Sclera, and Cornea

Rajeev Gokhale, Mandar V. Shah, Thomas F. Patton · Journal of Pharmaceutical Sciences · 1987 · 196 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Penetration Routes of Topically Applied Eye Medications

Marshall G. Doane, Allan Jensen, Claes H. Dohlman · American Journal of Ophthalmology · 1978 · 158 citations

Pharmacy, Ophthalmology, Pharmacology +14

Limits on Optimizing Ocular Drug Delivery

J.C. Keister, Eugene R. Cooper, Paul J. Missel et al. · Journal of Pharmaceutical Sciences · 1991 · 91 citations

Pharmacy, Ophthalmology, Pharmacology +12

Pharmacokinetics of Topically Applied Pilocarpine in the Albino Rabbit Eye

Michael C. Makoid, Joseph R. Robinson · Journal of Pharmaceutical Sciences · 1979 · 84 citations

Medicine, Pharmacokinetics, Pharmacology +14