Cholelithiasis in a 3-Week-Old Small Premature Infant

Abstract

Cholelithiasis is an extremely unusual finding in infancy. Hemolytic disease, infection, ileal disease, and anatomic deformity of bile ducts have been implicated.1 Recently, an association of prematurity, bronchopulmonary dysplasia, total parenteral nutrition, and furosemide has been reported.2 We have observed a small premature infant who developed cholelithiasis early in his hospital stay after a very short course of parenteral nutrition. CASE REPORT The patient was an 810-g male infant of 28 weeks' gestation (by Dubowitz examination) born to a 25-year-old gravida 2, para 1, abortus 1. The pregnancy was complicated only by premature rupture of membranes followed by labor. The mother had no fever or other signs or symptoms of infection prior to delivery.