Concepedia

Expression of pigment epithelium-derived factor in experimental choroidal neovascularization.

Reem Z. Renno, Ayman Youssri, Norman Michaud, Evangelos S. Gragoudas, Joan W. Miller

PubMed · 2002 · 77 citations · 20 references

Abstract

These results demonstrate an inverse correlation of expression of PEDF and formation of CNV in the experimental model and suggest that decreased expression of PEDF plays a permissive role in the formation of CNV. PEDF analogues may be a reasonable treatment strategy for CNV.

References

20

Prevalence of Age-related Maculopathy

Ronald Klein, Kathryn L.P. Linton · Ophthalmology · 1992 · 1.8K citations

, , +7

Pigment Epithelium-Derived Factor: A Potent Inhibitor of Angiogenesis

David W. Dawson, Olga V. Volpert, Paul Gillis et al. · Science · 1999 · 1.5K citations

The Beaver Dam Eye Study

Ronald Klein, Scot E. Moss, Kathryn L.P. Linton · Ophthalmology · 1992 · 1.3K citations

, , +4

Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor

Veronica Stellmach, Susan E. Crawford, Wei Zhou et al. · Proceedings of the National Academy of Sciences · 2001 · 357 citations · Full text

, , +13

Natural Course of Choroidal Neovascular Membranes Within the Foveal Avascular Zone in Senile Macular Degeneration

Susan B. Bressler, Neil M. Bressler, Stuart L. Fine et al. · American Journal of Ophthalmology · 1982 · 266 citations

, , +6