PubMed · 1953 · 15 citations · 3 references
MedicineHematologyOncologyHematologic OncologyHematopathologyRadiobiologyBone Marrow PathologyCell CharacterizationCellular Radiation ResponseHematologic MalignanciesRadiation TherapyBone Marrow CytologyBone Marrow DosimetryLeukemia PathologyMarrow Radiation ExposureRadiation Effects On The Hematopoietic SystemRadiation-induced Hematopoietic InjuryTherapeutic Radiation Conditioning
Summary 1.The average DNAP per cell for samples of bone marrow aspirated from sixteen patients with lymphocytic leukemia was 0.68 × 10 -9 mg. Similarly, the average cellular DNAP for fourteen patients with granulocytic leukemia was 0.82 × 10 -9 mg/cell. These values were considerably decreased following therapeutic x-radiation. 2.When the paired values of DNAP and RNAP per cell were plotted as points in a scatter diagram on a graph in which DNAP was abscissa and RNAP was ordinate, six lines of regression were developed whose coefficients of correlation were 0.28, 0.36, 0.45, 0.55, 0.69, and 0.85. These values correspond to those similarly derived for the lymphocytes of spleens of the C57BL mouse.
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