Molecular Basis for Action of Ionizing Radiations

Abstract

It is hoped that the general picture presented will provide a convenient framework within which to order many of the phenomena treated in radiobiology. The picture incorporates many of the concepts found useful in earlier theories, and also is simple, concrete, and easily visualized. From the theory, a reasonable estimate may be made of the effect of a given dose of radiatlon on a specific kind of molecule in a cell. Conversely, from the immediate effects produced by a certain dose, some estimate may be made of the mass of intracellular material which must be involved in the processes which are assayed for. It is felt that these advantages will suffice to carry the theory over its many difficulties and deficiencies until another and more encompassing viewpoint can be reached. (P.C.H.)