Selegiline as immunostimulant — a novel mechanism of action?

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease.

W. Sue T. Griffin, Laura Stanley, Lon R. White et al. · Proceedings of the National Academy of Sciences · 1989 · 1.8K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

Krzysztof Selmaj, Cedric S. Raine · Annals of Neurology · 1988 · 1.4K citations

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Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

Makio Mogi, Minoru Harada, Peter Riederer et al. · Neuroscience Letters · 1994 · 989 citations

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Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients

Makio Mogi, Minoru Harada, Tomoyshi Kondo et al. · Neuroscience Letters · 1994 · 860 citations

Life Sciences, Neurology, Neuroscience +13

Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta

Sunhee C. Lee, Weiwei Liu, Dennis W. Dickson et al. · The Journal of Immunology · 1993 · 800 citations

Medicine, Neurobiology, Neuroscience +17