RHINOVIRUS INFECTION IN CHILDREN WITH ACUTE LOWER RESPIRATORY DISEASE: EVIDENCE AGAINST ETIOLOGICAL IMPORTANCE

Abstract

The clinical, clinical laboratory, and viral aspects of 16 cases of lower respiratory disease in infants and children associated with rhinovirus isolation have been described. Rhinovirus isolations appeared to be as frequent in children without lower respiratory disease. Although the presence of concomitant infection with other viral agents made interpretation difficult, there was no conclusive evidence that the rhinoviruses were significant etiologic agents in children with lower respiratory disease severe enough to require hospitalization.