Comparison of a new PillCam™ SB2 video capsule versus the standard PillCam™ SB for detection of small bowel disease

Abstract

Background: Capsule endoscopy is the procedure of choice for many suspected small bowel diseases. PillCam™ small bowel (SB), has a high diagnostic yield. No improvements have been made on its optics since its introduction in 2002. Aim: To compare the diagnostic yield and quality of visualization of PillCam™ SB with that of a new small bowel endoscope (PillCam™ SB2) which has a larger angle of view and upgraded visual attributes. Methods: Twenty patients were randomized to undergo capsule enteroscopy with PillCam™ SB and PillCam™ SB2 a week apart. Results: Both procedures had a comparable diagnostic yield. However images from PillCam™ SB2 were found to be significantly better in regards of homogenous light exposure (P < 0.001), sharpness and resolution (P < 0.001), depth of view (P < 0.005), and overall impression (P < 0.0001). Conclusion: PillCam™ SB2 appears to be superior to the original PillCam™ SB in regard to quality of images obtained. Keywords: small bowel, capsule endoscopy, image quality, resolution