Concepedia

TIGIT negatively regulates inflammation by altering macrophage phenotype

Xi Chen, Puhan Lu, Lei Liu, Zemin Fang, Duan Wu, Zhelong Liu, Cong‐Yi Wang, Ping Zhou, Xuefeng Yu, Wentao He

Immunobiology · 2015 · 66 citations · 29 references

DOI

Concepts

References

29

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

F. Stephen Hodi, Steven O’Day, David F. McDermott et al. · New England Journal of Medicine · 2010 · 15.2K citations · Full text

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Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

Peter J. Murray, Judith E. Allen, Subhra K. Biswas et al. · Immunity · 2014 · 6.2K citations · Full text

, , +10

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

Xin Yu, Kristin Harden, Lino C. Gonzalez et al. · Nature Immunology · 2008 · 1.5K citations

, , +15

The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8 + T Cell Effector Function

Robert J. Johnston, Laëtitia Comps‐Agrar, Jason A. Hackney et al. · Cancer Cell · 2014 · 1.2K citations · Full text

, , +12

Macrophages Sequentially Change Their Functional Phenotype in Response to Changes in Microenvironmental Influences

Robert D. Stout, Chuancang Jiang, Bharati Matta et al. · The Journal of Immunology · 2005 · 956 citations · Full text

, , +14